Selenium Action in Pigs - Antioxidant and Anti-Inflammatory

What do you know about Selenium (Se) in pig diets? Se plays an essential role in thyroid hormone metabolism and the immune system in animals (Li et al., 2021). In the antioxidant defense system, Se protects cell membranes against free radicals that damage them (Zhan et al., 2007).

In recent studies, Selenium has been shown to protect the barrier and reduce inflammation in parts of the intestine (He et al., 2021), to reduce the inflammation induced by heat stress when combined with an enzyme (Le et al., 2019), and to reduce the temperature of growing pigs exposed to heat stress (Liu et al., 2017). Do you want to know more about Selenium action in pigs?

References:

He, Y., Liu, Y., Tang, J., Jia, G., Liu, G., Tian, G., Chen, X., Cai, J., Kang, B. Zhao, H. (2021) Selenium exerts protective effects against heat stress-induced barrier disruption and inflammation response in jejunum of growing pigs. Journal of the Science of Food and Agriculture, 102:496-504.

Le, H. H., Vidacs, E., Phillips, D. J., Zhao, W., Furness, J. B., Gabler, N. K., Renaudeau, D., Wijffels, G., Dunshea, F. R., DiGiacomo, K., Roura, E., Leury, B. J., Cottrell, J. J. (2019). Effect of selenium and superoxide dismutase supplementation on heat stressed pigs. Journal of Animal Science, 97 (2), p. 179.

Li, S., Sun, W., Zhang, K., Zhu, J., Jia, X., Guo, X., ... & Zhang, J. (2021). Selenium deficiency induces spleen pathological changes in pigs by decreasing selenoprotein expression, evoking oxidative stress, and activating inflammation and apoptosis. Journal of Animal Science and Biotechnology, 12, 65.

Zhan, X., Wang, M., Zhao, R., Li, W., Xu, Z. (2007). Effects of different selenium source on selenium distribution, loin quality, and antioxidant status in finishing pigs. Animal Feed Science and Technology, 132, 202-211.